Impaired Vagal Tone Function-Based Regulation of Systemic Inflammation in Patients With Neovascular Age-Related Macular Degeneration

Vagal tone is impaired in patients with nvAMD which disharmonizes with increased Tregs in the systemic circulation. These altered regulators may be the key to increased systemic inflammation, present in patients with nvAMD.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-10-08
DOI
https://doi.org/10.1167/iovs.66.13.16
Citations
1
Primary Topic
Vagus Nerve Stimulation Research
Type
article
Field-Weighted Citation Impact
0.84

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article

Impaired Vagal Tone Function-Based Regulation of Systemic Inflammation in Patients With Neovascular Age-Related Macular Degeneration

Jesper Mehlsen, Marie Krogh Nielsen, Torben Lykke Sørensen, Christophe Roubeix et al.
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article

Impaired Vagal Tone Function-Based Regulation of Systemic Inflammation in Patients With Neovascular Age-Related Macular Degeneration

Jesper Mehlsen, Marie Krogh Nielsen, Torben Lykke Sørensen, Christophe Roubeix, Charlotte Liisborg, Christopher Rue Molbech, Florian Sennlaub, Yousif Subhi, Marie-Louise Munch Bøegh
article en
1 citations

Abstract

Vagal tone is impaired in patients with nvAMD which disharmonizes with increased Tregs in the systemic circulation. These altered regulators may be the key to increased systemic inflammation, present in patients with nvAMD.

Investigative Ophthalmology & Visual ScienceVol. 66(13)
University of Copenhagen (DK), Centre National de la Recherche Scientifique (FR), Institut de la Vision (FR), Inserm (FR), University of Southern Denmark (DK), Rigshospitalet (DK), Sorbonne Université (FR), Zealand University Hospital (DK)
Apellis Pharmaceuticals, Region Sjælland
Openalex Percentile: Top 21%
Vagus Nerve Stimulation Research
0.84
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