Interaction between IGF2BP3 and RP11-480I12.5 facilitates proliferation and suppresses apoptosis in non-small cell lung cancer
RP11-480I12.5 interacted with IGF2BP3 to increase WDHD1 expression, promoting NSCLC cell proliferation and anti-apoptotic ability. Current findings elucidate how RP11-480I12.5 and IGF2BP3 interact at the molecular level, which has important implications for the progression of NSCLC.
Authors
- Rizhu Li (ORCID: https://orcid.org/0009-0004-2916-0275)
- Yuanxi Yao
- Jie Gao (ORCID: https://orcid.org/0000-0002-3366-3156)
- Fong Fong Liew (ORCID: https://orcid.org/0000-0001-9165-2343)
- Ye-peng Li
- Jinyuan Yi
- Hongming Chen (ORCID: https://orcid.org/0000-0002-2019-6923)
Institutions
- Mahsa University (MY)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Baise University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1186/s40001-025-03193-z
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00