Discovery of a resistant cohort to acute kidney injury: insights from patients with septic shock
Despite greater illness severity, AKI-resistant patients had similar mortality and length of stay as lower-risk patients but better outcomes than those with AKI. Studying these patients may reveal novel therapeutic targets for AKI prevention and treatment.
Authors
- John A. Kellum (ORCID: https://orcid.org/0000-0003-1995-2653)
- Dana Y. Fuhrman (ORCID: https://orcid.org/0000-0002-3672-7960)
- Samir M. Parikh (ORCID: https://orcid.org/0000-0002-1038-981X)
- Neil A. Hukriede (ORCID: https://orcid.org/0000-0002-9655-9030)
- Luca Molinari (ORCID: https://orcid.org/0000-0002-7372-4953)
- Towia Aron Libermann (ORCID: https://orcid.org/0000-0002-4006-8179)
Institutions
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- University of Pittsburgh (US)
- Southwestern Medical Center (US)
- Children's Hospital of Pittsburgh (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Critical Care
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1186/s13054-025-05647-6
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00