Application of Mendelian randomization to explore metabolic pathways in colorectal cancer

This study highlights genetically predicted metabolites associated with CRC risk, suggesting that metabolite panels and lipid-based biomarkers have potential for CRC risk assessment and early detection. However, further standardization and extensive validation are necessary before its clinical application.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2025-10-08
DOI
https://doi.org/10.1097/ms9.0000000000004020
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Application of Mendelian randomization to explore metabolic pathways in colorectal cancer

Tho Thi Anh Tran, Van Mai Truong, Tung Hoang
Annals of Medicine and Surgery
Cancer, Lipids, and Metabolism
article

Application of Mendelian randomization to explore metabolic pathways in colorectal cancer

Tho Thi Anh Tran, Van Mai Truong, Tung Hoang
article en

Abstract

This study highlights genetically predicted metabolites associated with CRC risk, suggesting that metabolite panels and lipid-based biomarkers have potential for CRC risk assessment and early detection. However, further standardization and extensive validation are necessary before its clinical application.

Annals of Medicine and SurgeryVol. 87(12)
Vietnam National University Ho Chi Minh City (VN), Hanoi Medical University (VN), Khanh Hoa General Hospital (VN)
Openalex Percentile: Top 65%
Cancer, Lipids, and Metabolism
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