Triterpene and Caffeoylquinic Acid Constituents Contribute to the Cognitive-Enhancing, but Not Anxiolytic, Effects of a Water Extract of Centella asiatica in Aged Mice
These results suggest that the TT and CQA present in CAW likely contribute to its previously reported amelioration of age-related cognitive changes, especially in learning and cognitive flexibility, while other constituents may be responsible for CAW's anxiolytic effects.
Authors
- Claudia S. Maier (ORCID: https://orcid.org/0000-0003-0743-8956)
- Jaewoo Choi (ORCID: https://orcid.org/0000-0001-6376-3089)
- Amala Soumyanath (ORCID: https://orcid.org/0000-0003-1569-6453)
- Nora E. Gray (ORCID: https://orcid.org/0000-0001-6848-859X)
- Wyatt Hack (ORCID: https://orcid.org/0009-0003-9589-0244)
- Luke Marney (ORCID: https://orcid.org/0000-0001-8117-8246)
- Seiji Koike (ORCID: https://orcid.org/0000-0001-9321-6502)
- Thuan Nguyen (ORCID: https://orcid.org/0000-0001-8137-6955)
- Jesús Miñano Martínez
- Lucas Kuhnau
- Arshia R. Sohal
Institutions
- Oregon State University (US)
- Oregon Health & Science University (US)
Publication Details
- Journal
- Nutrients
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3390/nu17193171
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging