Unraveling the Disease Mechanisms of Neuropathic Pain Through Constructing miRNA–mRNA Networks Based on a Rat Model
Four hub genes (Ptprc, C1qb, Fcgr2b, and Ccl2) may be potential biomarkers in NP pathogenesis, offering insights into its molecular mechanisms and suggesting therapeutic targets. C1qb knockdown is demonstrated to alleviate the NP progression through the NF-κB signaling pathway.
Authors
- Lingqi Yao
- Ming Liu
Institutions
- The First People's Hospital of Xiaoshan District, Hangzhou (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/brb3.70812
- Citations
- 1
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.91