Role of Gut Microbiome in Mental Health: Mushrooms as Natural Probiotic Stimulants

The gut microbiome is increasingly recognized as a regulator of both digestive and mental health through the gut-brain axis.Mushrooms, particularly Hericium erinaceus (Lion's Mane), have gained scientific interest for their rich bioactive profile and probioticstimulatory potential.Extracts of Lion's Mane contain polysaccharides, phenolics, and flavonoids that selectively enhance Lactobacillus growth, modulate gut microbiota, and protect the intestinal lining via antioxidant and anti-inflammatory effects.This dual activity strengthens the gut barrier while promoting neurotransmitter regulation, thereby linking gut health to emotional resilience.With their prebiotic and neuroprotective properties, medicinal mushrooms offer promising natural alternatives for future nutraceutical and mental health applications.

Publication Details

Journal
ACTA SCIENTIFIC MICROBIOLOGY
Published
2025-10-01
DOI
https://doi.org/10.31080/asmi.2025.08.1549
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of Gut Microbiome in Mental Health: Mushrooms as Natural Probiotic Stimulants

ACTA SCIENTIFIC MICROBIOLOGY
Gut microbiota and health
article

Role of Gut Microbiome in Mental Health: Mushrooms as Natural Probiotic Stimulants

article en

Abstract

The gut microbiome is increasingly recognized as a regulator of both digestive and mental health through the gut-brain axis.Mushrooms, particularly Hericium erinaceus (Lion's Mane), have gained scientific interest for their rich bioactive profile and probioticstimulatory potential.Extracts of Lion's Mane contain polysaccharides, phenolics, and flavonoids that selectively enhance Lactobacillus growth, modulate gut microbiota, and protect the intestinal lining via antioxidant and anti-inflammatory effects.This dual activity strengthens the gut barrier while promoting neurotransmitter regulation, thereby linking gut health to emotional resilience.With their prebiotic and neuroprotective properties, medicinal mushrooms offer promising natural alternatives for future nutraceutical and mental health applications.

ACTA SCIENTIFIC MICROBIOLOGY
Openalex Percentile: Top 75%
Gut microbiota and health
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