History of episodic heavy alcohol use predicts antidepressant effectiveness of ketamine
In patients with trMDD, history of episodic heavy drinking predicted antidepressant effectiveness of ketamine, but not ECT. These results may assist in patient selection for ECT vs. ketamine.
Authors
- Shan H. Siddiqi (ORCID: https://orcid.org/0000-0002-0967-9289)
- Stephen J. Seiner
- Joshua C. Brown (ORCID: https://orcid.org/0000-0003-0887-2746)
- Amanda Sedgewick
- Robert C. Meisner
- Aaishah R. Raquib (ORCID: https://orcid.org/0009-0001-4001-842X)
- Joseph J. Taylor (ORCID: https://orcid.org/0000-0002-9185-0427)
- Vy Nguyen
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Pacific Northwest University of Health Sciences (US)
- McLean Hospital (US)
- Massachusetts General Hospital (US)
- Western University of Health Sciences (US)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1007/s00213-025-06918-4
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00