TUMOR-ASSOCIATED MACROPHAGES: RELATIONSHIP WITH CLINICAL STATUS OF PATIENTS AND MOLECULAR BIOLOGICAL FEATURES OF BREAST CANCER
The topology and quantitative characteristics of macrophage infiltration in tumor tissue are closely associated with the extent of BC spread and the molecular profile of the neoplasms. The CD68+/CD163+ cell ratio may reflect the balance between antitumor and immunosuppressive mechanisms within the microenvironment and be considered a potential prognostic marker.
Authors
- Taras Zadvornyi (ORCID: https://orcid.org/0000-0003-3033-3976)
- I. Karacharova
- Anna Pavlova (ORCID: https://orcid.org/0000-0002-3974-5662)
- Oleksandr Mushii (ORCID: https://orcid.org/0000-0002-4666-9477)
- N Yu Lukianova (ORCID: https://orcid.org/0000-0002-3698-3868)
- V. BAZAS
Institutions
- R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (UA)
- Kyiv City Clinical Oncology Center (UA)
Publication Details
- Journal
- Experimental Oncology
- Published
- 2025-10-07
- DOI
- https://doi.org/10.15407/exp-oncology.2025.02.197
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Ministry of Education and Science of Ukraine