IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF MICRORNAS REGULATING HTERT
The current study provided a detailed procedure for identifying and verifying miRNAs against mRNAs, as well as highlighting the differential regulation of hTERT by specific miRNAs. It demonstrated that miRNA inhibition can modulate hTERT expression and cell proliferation, with potential implications for targeted cancer therapies. The strategy used in this study could also be applied to other genes for screening potential miRNAs.
Authors
- Abdul Wali (ORCID: https://orcid.org/0000-0001-8818-5369)
- Muhammad Mushtaq (ORCID: https://orcid.org/0000-0002-0896-3720)
- Imrana Niaz Sultan (ORCID: https://orcid.org/0000-0003-4891-7881)
- Afrasiab Khan Tareen (ORCID: https://orcid.org/0000-0001-5761-4044)
- Maham Ansari
- Rafiullah Rafiullah
Institutions
- Balochistan University of Information Technology, Engineering and Management Sciences (PK)
Publication Details
- Journal
- Experimental Oncology
- Published
- 2025-10-07
- DOI
- https://doi.org/10.15407/exp-oncology.2025.02.167
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Karolinska Institutet
- University of Illinois at Urbana-Champaign