INTERPLAY OF EPIGENETIC REGULATION OF KI-67 AND P53 BY MIR-21 AND MIR-34A IN CERVICAL INTRAEPITHELIAL NEOPLASIA
Our study demonstrates that the miR‑21, miR-34a, Ki-67, and p53 expression levels are significantly correlated with each other and are distinctly associated with the progression of CIN grades and HPV status, highlighting their potential as crucial CC biomarkers.
Authors
- N.F. Lygyrda
- V. Svintsitskyi
- Anna Kryzhanivska (ORCID: https://orcid.org/0000-0001-7720-7374)
- Т. Borikun (ORCID: https://orcid.org/0000-0001-7215-8315)
- A.V. Svintsitska
Institutions
- Ivano-Frankivsk National Medical University (UA)
- R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (UA)
- National Cancer Institute (UA)
Publication Details
- Journal
- Experimental Oncology
- Published
- 2025-10-07
- DOI
- https://doi.org/10.15407/exp-oncology.2025.02.223
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00