Retrospective analysis of [99mTc]Tc-HYNIC-PSMA single photon emission computed tomography CT in patients with prostate cancer

[ 99m Tc]Tc-PSMA SPECT/CT demonstrates promise as an alternative to MRI in the primary staging of prostate cancer, particularly in high SPECT SUV settings. While MRI remains more sensitive for local extension, PSMA SPECT may offer complementary value in comprehensive staging, especially in a resource-limited setting.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2025-10-07
DOI
https://doi.org/10.1097/mnm.0000000000002060
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Retrospective analysis of [99mTc]Tc-HYNIC-PSMA single photon emission computed tomography CT in patients with prostate cancer

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Retrospective analysis of [99mTc]Tc-HYNIC-PSMA single photon emission computed tomography CT in patients with prostate cancer

C. Samuelsson, Lotte Steffens, Michael Sunderland, Darin O’Keeffe, Stefan Gabrielson, Olof Jonmarker, Jyoti Puri
article en

Abstract

[ 99m Tc]Tc-PSMA SPECT/CT demonstrates promise as an alternative to MRI in the primary staging of prostate cancer, particularly in high SPECT SUV settings. While MRI remains more sensitive for local extension, PSMA SPECT may offer complementary value in comprehensive staging, especially in a resource-limited setting.

Nuclear Medicine CommunicationsVol. 47(1)
Christchurch Hospital (NZ), Karolinska Institutet (SE), University of Otago (NZ)
Openalex Percentile: Top 59%
Prostate Cancer Treatment and Research
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