A novel capsular operon and potentially conjugative plasmids in extensively drug-resistant urogenital Haemophilus parainfluenzae
The identification of a novel capsular operon in multidrug-resistant <i>H. parainfluenzae</i> strains highlights the species genetic plasticity and potential for increased virulence. These findings underscore the importance of ongoing surveillance in clinical settings to monitor the spread of antibiotic resistance and novel virulence factors, which may contribute to its pathogenicity and impact future treatment strategies.
Authors
- Rosa Maria E. Moreira da Costa (ORCID: https://orcid.org/0000-0001-6165-1649)
- Fé Tubau (ORCID: https://orcid.org/0000-0002-6416-6451)
- Mireia Rajadell
- Carmen Ardanuy (ORCID: https://orcid.org/0000-0003-0225-607X)
- Aída González-Díaz (ORCID: https://orcid.org/0000-0002-8326-1307)
- Sara Martí (ORCID: https://orcid.org/0000-0002-0405-2305)
- Mónica Ballestero-Téllez (ORCID: https://orcid.org/0000-0002-2222-246X)
- Marc Garreta (ORCID: https://orcid.org/0000-0003-3904-7896)
- M.Á. Domínguez (ORCID: https://orcid.org/0000-0003-3107-9586)
- Paul G. Higgins (ORCID: https://orcid.org/0000-0001-8677-9454)
- Laura Gisbert
- Kyriaki Xanthopoulou (ORCID: https://orcid.org/0000-0001-8591-8184)
- Lucía Saiz-Escobedo (ORCID: https://orcid.org/0009-0009-1993-0439)
- David Sánchez (ORCID: https://orcid.org/0000-0002-1490-9173)
- Irene Cadenas-Jiménez
Institutions
- University of Cologne (DE)
- Instituto de Salud Carlos III (ES)
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- University Hospital Mútua de Terrassa (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- German Center for Infection Research (DE)
- Mútua Terrassa (ES)
- University Hospital Cologne (DE)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fmicb.2025.1659538
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centres de Recerca de Catalunya
- Generalitat de Catalunya
- Instituto de Salud Carlos III
- European Regional Development Fund
- European Social Fund