Brain functional network topology and connectivity in primary blepharospasm

BSP is characterized by complex functional network disruptions, including impaired local information processing, altered nodal importance in key motor and relay hubs, and widespread connectivity changes. These findings reinforce BSP as a network disorder. These network alterations may serve as objective markers for disease progression and could guide the development of targeted neuromodulation therapies.

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Publication Details

Journal
Frontiers in Systems Neuroscience
Published
2025-10-08
DOI
https://doi.org/10.3389/fnsys.2025.1654795
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Brain functional network topology and connectivity in primary blepharospasm

Hualiang Li, Wen-Hui Li, Jian-Bin Hu, PingLei Pan et al.
Frontiers in Systems Neuroscience
Botulinum Toxin and Related Neurological Disorders
article

Brain functional network topology and connectivity in primary blepharospasm

Hualiang Li, Wen-Hui Li, Jian-Bin Hu, PingLei Pan, Shu Wang, Xin-Xin Yao, Siyu Gu
article en

Abstract

BSP is characterized by complex functional network disruptions, including impaired local information processing, altered nodal importance in key motor and relay hubs, and widespread connectivity changes. These findings reinforce BSP as a network disorder. These network alterations may serve as objective markers for disease progression and could guide the development of targeted neuromodulation therapies.

Frontiers in Systems NeuroscienceVol. 19
Yancheng Third People's Hospital (CN)
Jiangsu Commission of Health
Openalex Percentile: Top 60%
Botulinum Toxin and Related Neurological Disorders
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