Multimodal MRI-based radiomics in an ASD rat model: investigating brain structural changes and the neuroprotective effects of selenium
The cerebellum was a key region affected in ASD, whereas the visual-auditory cortex showed notable responses to selenium treatment. In conclusion, the multimodal radiomics model demonstrates high diagnostic efficacy, highlights the cerebellum as a key region affected in ASD, and suggests the visual-auditory cortex as a primary target of selenium intervention, enhancing predictive accuracy for structural and functional brain improvements post-treatment.
Authors
- Chengdong Li (ORCID: https://orcid.org/0000-0002-9680-3523)
- Jun Huang (ORCID: https://orcid.org/0000-0001-9190-9233)
- Xiaoan Zhang (ORCID: https://orcid.org/0009-0008-7820-566X)
- You‐Zhi Zhang (ORCID: https://orcid.org/0000-0002-1686-8651)
- Yikai Shu
Institutions
- Henan University of Science and Technology (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Third Affiliated Hospital of Zhengzhou University (CN)
- Baotou Medical College (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fnins.2025.1651220
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00