Serum levels of EphA2 are elevated in knee osteoarthritis and associated with disease severity
These findings suggest that EphA2 is closely associated with cartilage degradation, inflammation, oxidative stress, and ferroptosis in knee OA and may serve as a promising biomarker for disease diagnosis and progression monitoring.
Authors
- Mingyue Xiao (ORCID: https://orcid.org/0009-0000-2135-1545)
- Feng Shuang
- Lei Ji (ORCID: https://orcid.org/0000-0002-7563-9074)
- Wenbin Qian (ORCID: https://orcid.org/0000-0002-6138-5616)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Nantong Tumor Hospital (CN)
- Second People's Hospital of NanTong (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fmed.2025.1639458
- Primary Topic
- Axon Guidance and Neuronal Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00