Prognostic Impact of Advanced Lung Cancer Inflammation Index (ALI) on Immunotherapy Outcomes in Recurrent or Metastatic Nasopharyngeal Carcinoma: A Multicenter Post Hoc Analysis

Our findings suggest that pretreatment ALI as a promising prognostic biomarker for R/M NPC patients treated with ICIs. Given the exploratory post hoc nature of this analysis, the use of an empirically derived cutoff without external validation and the modest sample size of the matched cohort, these results warrant validation in future prospective studies.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-10-01
DOI
https://doi.org/10.2147/jir.s546584
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

Prognostic Impact of Advanced Lung Cancer Inflammation Index (ALI) on Immunotherapy Outcomes in Recurrent or Metastatic Nasopharyngeal Carcinoma: A Multicenter Post Hoc Analysis

Yiyan Pei, Zheran Liu, Shihong Xu, Junyou Ge et al.
Journal of Inflammation Research
Cancer Immunotherapy and Biomarkers
article

Prognostic Impact of Advanced Lung Cancer Inflammation Index (ALI) on Immunotherapy Outcomes in Recurrent or Metastatic Nasopharyngeal Carcinoma: A Multicenter Post Hoc Analysis

Yiyan Pei, Zheran Liu, Shihong Xu, Junyou Ge, Youneng Wei, Meiying Shao, Yan Qing, Song Ge, Miaoxia He
article en

Abstract

Our findings suggest that pretreatment ALI as a promising prognostic biomarker for R/M NPC patients treated with ICIs. Given the exploratory post hoc nature of this analysis, the use of an empirically derived cutoff without external validation and the modest sample size of the matched cohort, these results warrant validation in future prospective studies.

Journal of Inflammation ResearchVol. Volume 18
Sichuan University (CN), Kelun Group (China) (CN), Shenzhen Baoan High School Group (CN)
Natural Science Foundation of Sichuan Province
Openalex Percentile: Top 62%
Cancer Immunotherapy and Biomarkers
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