Factors associated with treatment failure after discharge in inpatients with schizophrenia spectrum disorders: A retrospective observational study
Antipsychotic polypharmacy at discharge was associated with treatment failure in patients with schizophrenia spectrum disorders. Additionally, trial overnight stays at home during hospitalization potentially contributed to preventing treatment failure. Therefore, preventing treatment failure in patients with schizophrenia spectrum disorder requires optimizing pharmacotherapy and implementing social and environmental adjustments, focusing on the post-discharge period.
Authors
- Shigeo Tsuchida
- Enami Sawayama
- Shigeki Kamitani (ORCID: https://orcid.org/0000-0002-1268-4652)
- Yuji Kenmotsu
- Nobuaki Kida
- Ken Inada (ORCID: https://orcid.org/0000-0002-3073-4588)
- Takaaki Hirooka (ORCID: https://orcid.org/0009-0008-6051-0148)
- Taiyo Nishikawa
- Kenji Kamimura
- Hiroyuki Muraoka (ORCID: https://orcid.org/0000-0003-1633-9079)
- Hirohito Kato
- Yuki Yoshimura (ORCID: https://orcid.org/0000-0002-1413-1963)
- Shoko Miura (ORCID: https://orcid.org/0000-0002-5776-8737)
- Shojiro Miyake (ORCID: https://orcid.org/0000-0001-7613-7634)
- Takayuki Yokoyama (ORCID: https://orcid.org/0000-0003-0646-4546)
- Yoshitaka Saito (ORCID: https://orcid.org/0000-0001-7159-8650)
- Ryutaro Suzuki
- Yuka Noguchi
- Satoru Oishi (ORCID: https://orcid.org/0000-0001-6577-0864)
- Kazuyuki Shimizu (ORCID: https://orcid.org/0000-0002-3679-0863)
- Yukihiro Tanno
Institutions
- Kitasato University Hospital (JP)
- Kitasato Institute Hospital (JP)
- Kitasato University (JP)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences Reports
- Published
- 2025-10-07
- DOI
- https://doi.org/10.1002/pcn5.70219
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00