Ameliorative Effects of Coenzyme Q10 Against Hypoxia‐Induced and Varicocele‐Associated Spermatogenesis Dysfunction in Rat
These findings suggest that CoQ10 improves chronic hypoxia-induced and varicocoele-related spermatogenesis dysfunction by reducing inflammation via the caspase1-IL1β-egr2 pathway. The study highlights CoQ10's protective role in male reproduction and its potential for treating male infertility linked to hypoxia and varicocoele.
Authors
- Mingliang Han
- Zhao-Yu Chen (ORCID: https://orcid.org/0000-0002-3772-5780)
- Yangyang Wan (ORCID: https://orcid.org/0009-0001-0214-4046)
- Hui Jiang (ORCID: https://orcid.org/0000-0002-6256-2733)
- Xin Chen (ORCID: https://orcid.org/0000-0002-9827-7731)
- Wenjing Liu (ORCID: https://orcid.org/0000-0002-0658-3601)
- Juan Hua (ORCID: https://orcid.org/0000-0002-9546-6203)
- Jun Shi (ORCID: https://orcid.org/0000-0003-4192-7091)
- Xiansheng Zhang (ORCID: https://orcid.org/0000-0003-4686-7702)
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- Peking University (CN)
- Peking University First Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Andrology
- Published
- 2025-10-07
- DOI
- https://doi.org/10.1111/andr.70130
- Citations
- 1
- Primary Topic
- Coenzyme Q10 studies and effects
- Type
- article
- Field-Weighted Citation Impact
- 0.81