Rapid bedside measurement of reactive oxygen species in neonates: a pilot study
The FLP-H4200 system is feasible for rapid and minimally invasive ROS measurement in neonates. Although no significant associations with clinical factors were identified, elevated ROS levels compared with those in adults suggest neonatal adaptation to oxidative stress. Further research is required to evaluate ROS dynamics progressively and their clinical use in neonatal disease prediction.
Authors
- Hiromichi Hamada (ORCID: https://orcid.org/0000-0002-8990-5265)
- Yoshiteru Osone (ORCID: https://orcid.org/0000-0001-5712-7019)
- Kimiko Kazumura (ORCID: https://orcid.org/0000-0002-8628-5785)
- Tadashi Shiohama (ORCID: https://orcid.org/0000-0003-0076-5882)
- Mamiko Endo
- Naoki Shimojo
- Y. Iijima
Institutions
- Hamamatsu Photonics (Japan) (JP)
- Chiba University (JP)
- Chiba University Hospital (JP)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fped.2025.1611197
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chiba University
- Japan Society for the Promotion of Science