Pannexin-1 hemichannels promote experimental colitis inflammation in a CD4+ T cell-specific manner
Together, our results suggest that PANX1 promotes colitis-associated pathogenic Th2-like responses and a possible link between these cells and colitis neutrophilia.
Authors
- Pooja Rani Mina (ORCID: https://orcid.org/0000-0003-2471-4967)
- Henrique Borges da Silva (ORCID: https://orcid.org/0000-0001-9424-3326)
- Bruna de Gois Macedo (ORCID: https://orcid.org/0000-0001-6907-1630)
- Chloe Leff (ORCID: https://orcid.org/0000-0002-9036-4099)
- Caio Loureiro Salgado (ORCID: https://orcid.org/0000-0002-4423-6723)
- Daniel Bihnam
Institutions
- Mayo Clinic Hospital (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1621353
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00