An implantable, intracerebral osmotic pump for convection-enhanced drug delivery in glioblastoma multiforme
This preliminary study demonstrated the feasibility of using an implantable, osmosis-driven pump to bypass the BBB and provide targeted delivery for treatment of GBM.
Authors
- Jill Shea (ORCID: https://orcid.org/0000-0002-8644-7772)
- John Y. Lee (ORCID: https://orcid.org/0000-0001-7328-1972)
- John McDaid (ORCID: https://orcid.org/0000-0002-1939-720X)
- Donald W. Graff (ORCID: https://orcid.org/0000-0001-9656-8765)
- Roberta Frigerio
- Aaron Barlow (ORCID: https://orcid.org/0000-0003-3262-5753)
- Daniil P. Aksenov (ORCID: https://orcid.org/0000-0003-4599-0290)
- A. K. M. Atique Ullah (ORCID: https://orcid.org/0000-0002-4545-2663)
- Bruce K. Gale (ORCID: https://orcid.org/0000-0001-5843-3464)
- George C. Bobustuc
- Reed Berlet
- N. K. Jha (ORCID: https://orcid.org/0000-0002-7944-8486)
- Azur Azapagic (ORCID: https://orcid.org/0000-0001-6111-1976)
- Matthew Walker (ORCID: https://orcid.org/0000-0003-4483-2258)
- Himanshu Sant
- Julian E. Bailes
- Jade Bookwalter
- Daniel Aliee
- Clint Bailes
Institutions
- Louisiana State University (US)
- NorthShore University HealthSystem (US)
- York University (CA)
- Queen's University (CA)
- Wilmington University (US)
- University of Utah (US)
- University of Chicago (US)
- Institute for Advanced Medical Research (US)
- Evanston Hospital (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fonc.2025.1676691
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63