Diffusion tensor imaging along the perivascular space may reveal potential pathological mechanisms underlying disease progression in primary open-angle glaucoma patients
The reduced ALPS index in POAG patients suggests impaired glymphatic clearance, which may impair metabolic clearance and contribute to RNFL damage, influencing disease progression.
Authors
- Wenli Tan (ORCID: https://orcid.org/0000-0001-7727-5772)
- Yanwen Huang (ORCID: https://orcid.org/0000-0002-4081-5488)
- Yu Ying (ORCID: https://orcid.org/0000-0002-2639-1877)
- Yilei Chen (ORCID: https://orcid.org/0000-0002-8811-3549)
- L. Yan
- Shuyu Xiao
- Zhigang Gong
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fneur.2025.1659200
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Science and Technology Commission of Shanghai Municipality