Development of Empty Sella in Neurosarcoidosis: A Case Report

Sarcoidosis is a multisystem inflammatory disorder characterized by non-caseating granulomas. Central nervous system (CNS) involvement occurs in 5–15% of cases, most commonly affecting the leptomeninges, cranial nerves, hypothalamus, or pituitary gland. Sellar sarcoidosis is rare, occurring in <1% of patients, and often presents with neuroendocrine manifestations, such as diabetes insipidus, hypopituitarism, or hyperprolactinemia. We report a case of systemic sarcoidosis with pituitary involvement that progressed to partial empty sella, a rarely reported sequela.