Drug-Induced PTH Resistance
PTH acts by binding to the PTH type 1 receptor (PTH1R) that leads to activation of the Gsα and intracellular cyclic adenosine monophosphate (cAMP) production, leading to a decrease in phosphate reabsorption, synthesis of the active form of vitamin D (1,25-dihydroxyvitamin D) and an increase in calcium reabsorption.
Publication Details
- Journal
- Egyptian Society of Diabetes and Lipidology Journal
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21608/esdlj.2025.456310
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00