Oocyte maturation triggers in high-responders: a report on 1,217 consecutive cycles

Ovarian hyperstimulation syndrome (OHSS) is a complication of medically assisted reproduction treatments that may require hospitalization. In the presence of high risk to develop OHSS, embryo transfer can be canceled and embryos frozen to be used in a later cycle. Alternatively, a newer drug, an agonist, can be used for egg trigger in association with endometrium special preparation. Some characteristics make women more susceptible to develop OHSS. In this group of patients, we observed that the use of an agonist as egg trigger did not decrease pregnancy outcomes and that the option of freezing all embryos followed by embryo transfer in a later cycle abolished development of OHSS with hospitalization.