Extensive Palatal Necrosis Due to Chrysomya bezziana Myiasis: A Detailed Case Report

Background: Myiasis, the infestation of live human tissue by dipterous larvae, is a rare condition in modern clinical practice but can present with severe complications in vulnerable individuals. Chrysomya bezziana, the Old World screwworm fly, is an obligate parasite known to cause aggressive tissue destruction, particularly in tropical regions. Case Presentation: We present a rare and severe case of extensive palatal necrosis caused by Chrysomya bezziana in a 62-year-old immunocompromised patient from a rural area. The patient presented with facial swelling, halitosis, and a necrotic lesion in the palate, initially misdiagnosed as a fungal infection. Direct examination revealed numerous live larvae within the necrotic tissue. Imaging studies ruled out deeper craniofacial involvement. Management included mechanical debridement, systemic antibiotics, and antiparasitic therapy, followed by reconstructive surgery. Conclusion: This case highlights the importance of considering myiasis in differential diagnoses of orofacial necrosis, especially in endemic regions and among immunocompromised or neglected populations. Early recognition and appropriate intervention are crucial to prevent extensive tissue damage and systemic complications.