Persistent Increased Plasmacytoid Dendritic Cells and Inflammation in People With HIV Years After Tuberculosis
A proinflammatory milieu and immune cell gene expression changes mediated by TNF persist in people living with HIV even years after TB cure. If the differences are pre-existing risk factors or establish during the natural history of HIV and TB infections is still to be determined.
Authors
- Jean W. Pape (ORCID: https://orcid.org/0000-0002-2948-2774)
- Alexandra Apollon
- Yvetot Joseph
- Paul Zumbo (ORCID: https://orcid.org/0000-0001-7234-2024)
- Daniel W. Fitzgerald (ORCID: https://orcid.org/0000-0003-1765-0598)
- Alicia Alonso (ORCID: https://orcid.org/0000-0002-2730-7470)
- Doron Betel (ORCID: https://orcid.org/0000-0002-8006-7752)
- Kathryn Dupnik (ORCID: https://orcid.org/0000-0001-7100-2917)
- Maureen M. Ward
Institutions
- Cornell University (US)
- Gheskio Centers (HT)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1093/infdis/jiaf499
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Weill Cornell Medical College
- National Center for Advancing Translational Sciences