The Role of Pan-Immune Inflammation Value in Predicting Saphenous Vein Graft Patency After Coronary Artery Bypass Surgery

Aim: In this study, it was aimed to investigate the predictive value of pan-immune-inflammation value (PIV) in postoperative saphenous vein graft patency (SVG). Materials and Methods:Data of 300 patients with coronary artery bypass grafting (CABG) who underwent angiography between January 2022 and January 2024 were retrospectively analyzed.These patients were divided into two groups according to the presence of 50% or more stenosis in SVG (Group 1: SVG patent, Group 2: SVG not patent).We investigated PIV, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio, systemic inflammation response index, and systemic inflammation index.The study aimed to investigate whether there was a difference in inflammation indexes between the groups. Results:The cut-off value of PIV >444 was associated with 72% sensitivity and 62% specificity to predict SVG disease (SVGD) in patients with CABG.Multivariate logistic regression analysis showed that PLR and PIV levels were independent predictors of SVGD, respectively [odds ratio (OR): 1.025; 95% confidence interval (CI): 1.008-1.042;p=0.003)] and (OR: 1.012; 95% CI: 1.000-1.015;p=0.004). Conclusion:PIV and PLR may be useful predictors of SVGD, which can be easily estimated from blood tests in routine practice.As a novel inflammatory biomarker, PIV may serve as a valuable tool for risk stratification and long-term follow up in this patient population.