The Preanalytical Process Matters: Impact of Blood Collection Tubes on the Measurement of Vitamin D Using Liquid Chromatography Tandem Mass Spectrometry
These findings highlight the need to evaluate blood collection tubes from various manufacturers prior to the clinical implementation of LC-MS/MS measurements. Because LC-MS/MS has unique potential error sources, our results indicate the importance in utilizing LC-MS/MS international standards to ensure accurate and reliable results in clinical laboratories.
Authors
- Sae Ochi (ORCID: https://orcid.org/0000-0003-4133-3170)
- Yuichi Ikeda (ORCID: https://orcid.org/0000-0002-9929-3813)
- Akihiro Kunisawa
- Nobuhiro Hanafusa
- Masaki Miyasaka (ORCID: https://orcid.org/0000-0001-5490-7925)
- Yutaka Furutani (ORCID: https://orcid.org/0000-0002-2945-0166)
- Daisuke Kawakami (ORCID: https://orcid.org/0000-0002-6991-9109)
- Tomokazu Matsuura (ORCID: https://orcid.org/0000-0002-7963-3518)
- Reiko Kisugi
- Ayasa Tajima (ORCID: https://orcid.org/0009-0007-8775-6298)
- Tsuyoshi Nakanishi (ORCID: https://orcid.org/0000-0002-5886-7438)
- Hiroyasu Miyamoto
Institutions
- Jikei University School of Medicine (JP)
- The Jikei University Hospital (JP)
- Shimadzu (Japan) (JP)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1093/jalm/jfaf141
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00