Evaluating the necessity of prophylactic lateral neck dissection in medullary thyroid carcinoma based on preoperative calcitonin levels: a multicenter retrospective cohort study
Prophylactic LND did not significantly impact long-term oncologic outcomes in MTC patients without clinically evident lateral LN metastasis, even among those with elevated preoperative calcitonin levels above 200 pg/mL. Although prophylactic LND was associated with higher biochemical cure rates, this did not translate into reduced recurrence rates or improved survival. Routine prophylactic LND may not be necessary, and the decision to perform it should be carefully individualized based on patient-specific factors.
Authors
- Byung-Chang Kim (ORCID: https://orcid.org/0000-0002-9634-403X)
- Ki-Wook Chung
- Shin Jeong Pak (ORCID: https://orcid.org/0000-0002-9097-7135)
- Jong Ju Jeong (ORCID: https://orcid.org/0000-0002-4155-6035)
- Yu‐Mi Lee (ORCID: https://orcid.org/0000-0002-8183-2604)
- Tae‐Yon Sung
- Won Bae Kim (ORCID: https://orcid.org/0000-0003-4544-1750)
- Douk Kwon
Institutions
- Ulsan College (KR)
- Yonsei University (KR)
- Eulji University (KR)
- Severance Hospital (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Hanyang University Seoul Hospital (KR)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1097/js9.0000000000003557
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.29