ELAVL1 Stabilizes HMOX1 mRNA to Drive Ferroptosis in Diabetic Retinopathy

HMOX1 is critical for ferroptosis-mediated retinal damage in DR, and ELAVL1 promotes ferroptosis predominantly by stabilizing HMOX1 mRNA.

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Publication Details

Journal
Diabetes Metabolic Syndrome and Obesity
Published
2025-10-01
DOI
https://doi.org/10.2147/dmso.s536325
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

ELAVL1 Stabilizes HMOX1 mRNA to Drive Ferroptosis in Diabetic Retinopathy

Cun-xi Ye, Qiannan Chai, Yanjun Gao, Wenjing Zhao
Diabetes Metabolic Syndrome and Obesity
Ferroptosis and cancer prognosis
article

ELAVL1 Stabilizes HMOX1 mRNA to Drive Ferroptosis in Diabetic Retinopathy

Cun-xi Ye, Qiannan Chai, Yanjun Gao, Wenjing Zhao
article en

Abstract

HMOX1 is critical for ferroptosis-mediated retinal damage in DR, and ELAVL1 promotes ferroptosis predominantly by stabilizing HMOX1 mRNA.

Diabetes Metabolic Syndrome and ObesityVol. Volume 18
Hebei Medical University (CN), Second Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 60%
Ferroptosis and cancer prognosis
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ELAVL1 Stabilizes HMOX1 mRNA to Drive Ferroptosis in Diabetic Retinopathy — Cun-xi Ye, Qiannan Chai, et al. · Diabetes Metabolic Syndrome and Obesity (2025) | TGRS Research Map | TGRS