Fungal Glycoside Hydrolases shape the Leaf Microbiome and mediate Interkingdom Microbial Antagonism

Cross-inhibition events within the associated bacterial community shape A. laibachii infection outcome Curtobacterium sp. rescues A. laibachii inhibition by MbA and leads to GH25 upregulation MbA inhibits A. laibachii via GH25Bacteria associated with A. laibachii are targeted by GH25 GH25 mediates an antagonistic interplay between bacteria, oomycete and yeast OutlookWe aim to further understand the influence of GH25 on the phyllosphere microbiome.Moreover, we want to unravel the biochemical specificity of GH25 among different orthologues.