Endoscopic Transsphenoidal Selective Resection of the Medial Wall of the Cavernous Sinus for the Treatment of Functional Pituitary Adenomas

Abstract To investigate the efficacy of endoscopic transsphenoidal selective resection of the medial wall of the cavernous sinus (MWCS) for the treatment of functional pituitary adenomas (FPAs). Clinical data of fifteen patients with FPAs were retrospectively analyzed. The MWCS on the side of the tumor was surgically resected. In this study of fifteen patients, endocrine remission was observed in thirteen cases (86.7%) after surgery, and tumor cells in the MWCS were found in ten (66.7%) cases. No serious postoperative complications occurred in any patient. For FPAs characterized as Knosp grades 0 to 3, if there is no clear pseudocapsule or normal pituitary between the tumor and the MWCS during the operation, consideration of removal of the MWCS on that side may contribute to improved postoperative remission rates.