Estimating the potential economic and health impact of integrated genomic surveillance in a hospital setting
Our integrated genomic surveillance approach reveals previously unexplored transmission landscapes. We discovered that transmission is widespread, varies between species, and is not limited to resistant isolates. Our results emphasise the potential of integrated genomic surveillance, the identification of local transmission hotspots, potential greater savings by including susceptible isolates, and an incremental cost-effectiveness ratio classification by pathogen species.
Authors
- Karen Leth Nielsen (ORCID: https://orcid.org/0000-0002-7912-1985)
- Frederik Boëtius Hertz (ORCID: https://orcid.org/0000-0003-0888-4616)
- Susanne Häußler (ORCID: https://orcid.org/0000-0001-6141-9102)
- Rasmus L. Marvig (ORCID: https://orcid.org/0000-0002-5267-3173)
- Christian S. Jensen (ORCID: https://orcid.org/0000-0002-9530-1919)
- Michael Søgaard Jørgensen (ORCID: https://orcid.org/0000-0001-6646-7250)
- Jenny Dahl Knudsen (ORCID: https://orcid.org/0000-0002-8699-9956)
- Jakob Erdmann (ORCID: https://orcid.org/0000-0002-4195-4535)
- Asger Nellemann Rasmussen (ORCID: https://orcid.org/0009-0006-3819-5896)
- Steen Christian Rasmussen
- Dmytro Strunin
- Theiss Bendixen
- Roshkan Srinathan
Institutions
- University of Copenhagen (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Chr. Hansen (Denmark) (DK)
- Helmholtz Centre for Infection Research (DE)
- Center for Experimental and Clinical Infection Research (DE)
Publication Details
- Journal
- Clinical Microbiology and Infection
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.cmi.2025.09.021
- Citations
- 3
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 5.64