Squamous Cell Carcinoma Arising in Chronic Hidradenitis Suppurativa

While chronic inflammation is a well-established risk factor for carcinogenesis, the varied cutaneous manifestations of long-standing hidradenitis suppurativa (HS) can delay early detection of squamous cell carcinoma (SCC). Here, we present the clinical vignette of a patient with rapidly progressive treatment refractory HS paired with striking interval imaging demonstrating the development of superimposed cutaneous SCC.