Hormonal contraceptives and the risk of meningioma: A Swedish register-based case-control study
This large register-based case-control study show a strong association between injectable hormonal contraceptives containing medroxyprogesterone and meningioma risk. The results add to the growing body of evidence of an association between meningiomas and progestins in general and the strong, consistent associations suggest a causal role of injectable medroxyprogesterone in meningioma growth. Our results correspond to 2 additional cases of meningioma per 10 000 women exposed to medroxyprogesterone per year.
Authors
- Helena Kopp Kallner (ORCID: https://orcid.org/0000-0001-7184-9165)
- Tiit Illimar Mathiesen (ORCID: https://orcid.org/0000-0001-9463-1919)
- Maria Feychting (ORCID: https://orcid.org/0000-0002-5101-0060)
- Giorgio Tettamanti
- Hanna Mogensen (ORCID: https://orcid.org/0000-0001-5195-8065)
- Xiaochen Shu (ORCID: https://orcid.org/0000-0002-4933-5851)
Institutions
- Uppsala University (SE)
- University of Copenhagen (DK)
- Danderyds sjukhus (SE)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- Soochow University (CN)
- Glanrhyd Hospital (GB)
- IT University of Copenhagen (DK)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1093/neuonc/noaf228
- Citations
- 3
- Primary Topic
- Heusler alloys: electronic and magnetic properties
- Type
- article
- Field-Weighted Citation Impact
- 1.28
Funders
- Teva Pharmaceutical Industries
- Vetenskapsrådet
- H. Lundbeck A/S
- Nordic Pharma Group