Preoperative N-terminal pro-B-type natriuretic peptide and postoperative acute kidney injury in cardiac surgery: a mediation analysis of intraoperative hypotension

IOH mediates a statistically significant portion of the relationship between increased preoperative NT-proBNP and postoperative AKI in cardiac surgery patients. Further research is needed to investigate whether optimizing anesthesia management by alleviating IOH could reduce the risk of AKI in patients with increased preoperative NT-proBNP.

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Publication Details

Journal
International Journal of Surgery
Published
2025-10-03
DOI
https://doi.org/10.1097/js9.0000000000003564
Primary Topic
Cardiac, Anesthesia and Surgical Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Preoperative N-terminal pro-B-type natriuretic peptide and postoperative acute kidney injury in cardiac surgery: a mediation analysis of intraoperative hypotension

Lin Zhu, Xiaofan Huang, Yan Cui, Shuqi Meng et al.
International Journal of Surgery
Cardiac, Anesthesia and Surgical Outcomes
article

Preoperative N-terminal pro-B-type natriuretic peptide and postoperative acute kidney injury in cardiac surgery: a mediation analysis of intraoperative hypotension

Lin Zhu, Xiaofan Huang, Yan Cui, Shuqi Meng, Keliang Xie, Shuaijie Pei, Jianfeng Liu, Xiaoli Yu
article en

Abstract

IOH mediates a statistically significant portion of the relationship between increased preoperative NT-proBNP and postoperative AKI in cardiac surgery patients. Further research is needed to investigate whether optimizing anesthesia management by alleviating IOH could reduce the risk of AKI in patients with increased preoperative NT-proBNP.

International Journal of SurgeryVol. 112(1)
Xuzhou Medical College (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 58%
Cardiac, Anesthesia and Surgical Outcomes
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Preoperative N-terminal pro-B-type natriuretic peptide and postoperative acute kidney injury in cardiac surgery: a mediation analysis of intraoperative hypotension — Lin Zhu, Xiaofan Huang, et al. · International Journal of Surgery (2025) | TGRS Research Map | TGRS