Development of a UPLC-MS/MS method for simultaneous quantification of 7 bile acids in feces: application to UC mice
The method established by our research institute is simple to operate, with high accuracy, sensitivity, and strong specificity, enabling rapid quantification of seven bile acid components in mouse feces. Fecal analysis revealed that bile acid alterations are associated with UC progression and suggesting AOE's therapeutic potential.
Authors
- Yinfeng Tan (ORCID: https://orcid.org/0000-0002-8629-8463)
- Yonghui Li (ORCID: https://orcid.org/0000-0003-0298-7294)
- Hailong Li (ORCID: https://orcid.org/0000-0003-0652-6655)
- Junyan Cao
- Yun‐Juan Chang (ORCID: https://orcid.org/0000-0003-2688-6391)
Institutions
- Haikou Experimental Station (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1080/17576180.2025.2571025
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00