Solitary fibrous tumor of the prostate: Case report and literature review

Solitary fibrous tumor (SFT) of the prostate is a rare mesenchymal neoplasm with only a few cases reported. Its clinical presentation often mimics benign prostatic hyperplasia, and imaging findings are nonspecific. Diagnosis relies on histopathology and immunohistochemistry, particularly STAT6 nuclear expression. Most cases follow a benign course, but some may exhibit aggressive behavior. Complete surgical resection with clear margins is the treatment of choice, with no established role for adjuvant therapy. This report discusses a case of prostatic SFT, emphasizing its diagnostic challenges, imaging findings, and surgical management, contributing to the limited literature on this rare entity.

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Publication Details

Journal
Urology Case Reports
Published
2025-09-23
DOI
https://doi.org/10.1016/j.eucr.2025.103207
Primary Topic
Soft tissue tumor case studies
Type
article
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article

Solitary fibrous tumor of the prostate: Case report and literature review

Alessandro Vengjer, A Ortiz, Matheus Miranda Paiva, Kátia Ramos Moreira Leite et al.
Urology Case Reports
Soft tissue tumor case studies
article

Solitary fibrous tumor of the prostate: Case report and literature review

Alessandro Vengjer, A Ortiz, Matheus Miranda Paiva, Kátia Ramos Moreira Leite, André Segura da Motta, Eloi Guilherme Provinciali Moccellin, Raphael Oliveira Emerick Constantino
article en

Abstract

Solitary fibrous tumor (SFT) of the prostate is a rare mesenchymal neoplasm with only a few cases reported. Its clinical presentation often mimics benign prostatic hyperplasia, and imaging findings are nonspecific. Diagnosis relies on histopathology and immunohistochemistry, particularly STAT6 nuclear expression. Most cases follow a benign course, but some may exhibit aggressive behavior. Complete surgical resection with clear margins is the treatment of choice, with no established role for adjuvant therapy. This report discusses a case of prostatic SFT, emphasizing its diagnostic challenges, imaging findings, and surgical management, contributing to the limited literature on this rare entity.

Urology Case ReportsVol. 63
Universidade de Ribeirão Preto (BR), Irmandade da Santa Casa de Misericórdia de São Paulo (BR), Santa Casa de Misericórdia de Marília (BR), Universidade Metropolitana de Santos (BR), Hospital Universitário da Universidade de São Paulo (BR), Faculdade de Medicina do ABC (BR)
Openalex Percentile: Top 59%
Soft tissue tumor case studies
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