Antibodies to Tick Salivary Antigens AV422 and Calreticulin in Patients With Spotted Fever Group Rickettsioses and Other Febrile Illnesses in Northern Tanzania
In the acute phase of febrile illness, measurement of calreticulin antibody, a proposed marker for tick exposure, was higher in patients with confirmed tick-borne illness and had reasonable diagnostic test characteristics.
Authors
- Deng B. Madut (ORCID: https://orcid.org/0000-0003-4023-3928)
- Halie K. Miller (ORCID: https://orcid.org/0000-0001-5004-0789)
- John A. Crump (ORCID: https://orcid.org/0000-0002-4529-102X)
- Matthew P. Rubach (ORCID: https://orcid.org/0000-0001-5262-1421)
- Jo E. B. Halliday (ORCID: https://orcid.org/0000-0002-1329-9035)
- Ganga S. Moorthy (ORCID: https://orcid.org/0000-0003-3191-1117)
- Venance P. Maro (ORCID: https://orcid.org/0000-0003-3838-0312)
- Jamie L. Perniciaro (ORCID: https://orcid.org/0000-0002-7613-8984)
- Sarah Cleaveland (ORCID: https://orcid.org/0000-0002-0456-0959)
- Bingileki F. Lwezaula (ORCID: https://orcid.org/0000-0003-2909-9705)
- Blandina Theophil Mmbaga (ORCID: https://orcid.org/0000-0002-5550-1916)
- Bessie H Blocher (ORCID: https://orcid.org/0000-0003-2164-1141)
- William L. Nicholson (ORCID: https://orcid.org/0000-0002-2215-6837)
Institutions
- National University of Singapore (SG)
- Duke University (US)
- Moshi Co-operative University (TZ)
- Clinical Research Institute (US)
- National Center for Emerging and Zoonotic Infectious Diseases (US)
- Duke Institute for Health Innovation (US)
- Duke Medical Center (US)
- Duke-NUS Medical School (SG)
- Kilimanjaro Christian Medical Centre (TZ)
- Duke University Health System (US)
- St. Francis Referral Hospital (TZ)
- University of Glasgow (GB)
- University of Otago (NZ)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1093/infdis/jiaf506
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Bill and Melinda Gates Foundation
- Research Councils UK
- Department for International Development
- National Institutes of Health
- Directorate for Biological Sciences
- Biotechnology and Biological Sciences Research Council
- National Institute of Allergy and Infectious Diseases