SGLT2 Inhibitors in Heart Failure with Reduced Ejection Fraction: A Retrospective Cohort Analysis of Sex-Specific Cardiovascular Outcomes

Among HFrEF patients treated with SGLT2is, males experienced lower risks of HF events, hospitalizations, and renal failure compared to females, despite similar mortality. Further research is needed to understand and address sex-specific disparities in HFrEF management.

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Publication Details

Journal
Current Cardiology Reviews
Published
2025-10-02
DOI
https://doi.org/10.2174/011573403x394902250911111958
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

SGLT2 Inhibitors in Heart Failure with Reduced Ejection Fraction: A Retrospective Cohort Analysis of Sex-Specific Cardiovascular Outcomes

Kwan Lee, Chadi Ayoub, Beani Forst, Hoang Nhat Pham et al.
Current Cardiology Reviews
Diabetes Treatment and Management
article

SGLT2 Inhibitors in Heart Failure with Reduced Ejection Fraction: A Retrospective Cohort Analysis of Sex-Specific Cardiovascular Outcomes

Kwan Lee, Chadi Ayoub, Beani Forst, Hoang Nhat Pham, Julie Rosenthal, Ramzi Ibrahim, Reza Arsanjani, Patrick Sarkis, Mahmoud Hassan Abdelnabi, Hashim M. AlHammouri, Rahmeh Al-Asmar, Steven J. Lester
article en

Abstract

Among HFrEF patients treated with SGLT2is, males experienced lower risks of HF events, hospitalizations, and renal failure compared to females, despite similar mortality. Further research is needed to understand and address sex-specific disparities in HFrEF management.

Current Cardiology ReviewsVol. 22
University of Jordan (JO), Mayo Clinic (US), University of Arizona (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 63%
Diabetes Treatment and Management
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