Characterization of the Cellular Immune Response to Group B Streptococcal Vaginal Colonization
Taken together, this work characterizes FGT cellular immunity and suggests that GBS colonization does not elicit a significant immune response, which may be a bacterial directed adaptive outcome. However, certain FGT immune cells, such as neutrophils and ɣδ T cells, contribute to host defense and control of GBS colonization.
Authors
- Brady L. Spencer (ORCID: https://orcid.org/0000-0003-4374-6403)
- Rebecca L. O’Brien (ORCID: https://orcid.org/0000-0002-9075-7984)
- Kelly S. Doran (ORCID: https://orcid.org/0000-0003-4232-6837)
- Laurent Gapin (ORCID: https://orcid.org/0000-0001-9730-5174)
- Stephanie M Marroquin (ORCID: https://orcid.org/0000-0002-8668-2203)
- Dustin T. Nguyen
Institutions
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Journal of Innate Immunity
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1159/000548044
- Citations
- 1
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Neurological Disorders and Stroke