Appendiceal mucocele presenting as acute appendicitis

Background: Appendiceal mucocele represents cystic expansion of the appendix caused by mucin accumulation, frequently mimicking acute appendicitis clinically. Case Report: We present a case of elderly male who developed periumbilical discomfort, loss of appetite, and demonstrated positive rebound tenderness on examination. Imaging studies revealed an enlarged, perforated appendix which was initially interpreted as acute appendicitis. Intraoperatively, a significantly distended appendix measuring 4.0 x 2.5 cm containing thick, gelatinous mucoid contents was identified. Histological analysis established the diagnosis of appendiceal mucocele with mucin deposition and clear surgical margins. Postoperative recovery was uneventful. Complete surgical excision remains the primary treatment modality, with minimally invasive techniques being suitable for selected patients, although conventional open surgery was chosen in this instance due to perforation risk. Conclusion: This case emphasizes the importance of preoperative radiological assessment, good surgical technique to prevent rupture with subsequent pseudomyxoma peritonei, and definitive histopathological diagnosis.

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Publication Details

Journal
International Journal of Pathology
Published
2025-09-29
DOI
https://doi.org/10.59736/ijp.23.03.974
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Appendiceal mucocele presenting as acute appendicitis

Muhammad Daud
International Journal of Pathology
Intraperitoneal and Appendiceal Malignancies
article

Appendiceal mucocele presenting as acute appendicitis

Muhammad Daud
article en

Abstract

Background: Appendiceal mucocele represents cystic expansion of the appendix caused by mucin accumulation, frequently mimicking acute appendicitis clinically. Case Report: We present a case of elderly male who developed periumbilical discomfort, loss of appetite, and demonstrated positive rebound tenderness on examination. Imaging studies revealed an enlarged, perforated appendix which was initially interpreted as acute appendicitis. Intraoperatively, a significantly distended appendix measuring 4.0 x 2.5 cm containing thick, gelatinous mucoid contents was identified. Histological analysis established the diagnosis of appendiceal mucocele with mucin deposition and clear surgical margins. Postoperative recovery was uneventful. Complete surgical excision remains the primary treatment modality, with minimally invasive techniques being suitable for selected patients, although conventional open surgery was chosen in this instance due to perforation risk. Conclusion: This case emphasizes the importance of preoperative radiological assessment, good surgical technique to prevent rupture with subsequent pseudomyxoma peritonei, and definitive histopathological diagnosis.

International Journal of PathologyVol. 23(3)
Lady Reading Hospital (PK)
Openalex Percentile: Top 56%
Intraperitoneal and Appendiceal Malignancies
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