Efficacy of Tacrolimus Plus Prednisone as Long-Term Immunosuppressive Therapy for Chronic Inflammatory Demyelinating Polyneuropathy: A Retrospective Cohort Study
Tacrolimus plus prednisone therapy demonstrated superior clinical outcomes compared to prednisone monotherapy in CIDP maintenance treatment, including accelerated symptomatic improvement, reduced relapse risk, and facilitated corticosteroid tapering. The combination regimen maintained an acceptable safety profile without serious adverse events, supporting its corticosteroid-sparing role in CIDP management.
Authors
- Yuwei Da (ORCID: https://orcid.org/0000-0002-0318-148X)
- Wenjia Zhu (ORCID: https://orcid.org/0000-0003-1397-4544)
- Min Xu (ORCID: https://orcid.org/0000-0002-0982-057X)
- Xinmei Wen
- Min Wang (ORCID: https://orcid.org/0000-0001-6706-3418)
- Yan Lu (ORCID: https://orcid.org/0000-0003-2211-9515)
- Hai Chen (ORCID: https://orcid.org/0000-0003-1605-8082)
- Li Di (ORCID: https://orcid.org/0000-0001-6359-7455)
Institutions
- Capital Medical University (CN)
Publication Details
- Journal
- ImmunoTargets and Therapy
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/itt.s536989
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China