New Genetic Loci Implicated in Cardiac Morphology and Function Using Three-Dimensional Population Phenotyping
These findings provide a comprehensive description of the pathways that orchestrate heart development and cardiac remodeling. These data highlight the role that cardiomyopathy-associated genes have on the regulation of spatial adaptations in those without known disease.
Authors
- James S. Ware (ORCID: https://orcid.org/0000-0002-6110-5880)
- Sean L. Zheng (ORCID: https://orcid.org/0000-0002-5762-6392)
- Wenjia Bai (ORCID: https://orcid.org/0000-0003-2943-7698)
- Declan P. O’Regan (ORCID: https://orcid.org/0000-0002-0691-0270)
- Antonio de Marvao (ORCID: https://orcid.org/0000-0001-9095-5887)
- Kathryn A. McGurk (ORCID: https://orcid.org/0000-0002-5445-6906)
- Chang Lu (ORCID: https://orcid.org/0000-0001-6304-2820)
- Paolo Inglese (ORCID: https://orcid.org/0000-0001-6179-9643)
Institutions
- Broad Institute (US)
- Imperial College Healthcare NHS Trust (GB)
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Hammersmith Hospital (GB)
- Harefield Hospital (GB)
- British Heart Foundation (GB)
- Lung Institute (US)
- Imperial College London (GB)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1161/circgen.124.005116
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00