Long‐term prognostic implications of type 2 diabetes mellitus in colorectal cancer patients
Our findings highlight the compounded negative impact of T2DM and depression on overall survival in CRC patients. Their combined presence significantly worsens prognosis, underscoring the need for integrated care approaches that address both physical and mental health. Future research should explore targeted interventions for these comorbidities to improve long-term outcomes and quality of life in this high-risk population.
Authors
- Urko Aguirre (ORCID: https://orcid.org/0000-0002-8049-3030)
- Esperanza Varela‐Moreno (ORCID: https://orcid.org/0000-0001-8952-0608)
- Julia Alcaide (ORCID: https://orcid.org/0000-0002-9301-1387)
- Dieter Morales-García (ORCID: https://orcid.org/0000-0002-6258-5150)
- Hatim Boughanem (ORCID: https://orcid.org/0000-0001-7743-311X)
- Marisa Baré
- Marilina García‐Aranda (ORCID: https://orcid.org/0000-0003-3759-4044)
- José María Quintana (ORCID: https://orcid.org/0000-0003-2170-7876)
- Maximino Redondo (ORCID: https://orcid.org/0000-0001-5559-4246)
- Marta Robles‐Lasarte
- Francisco Rivas‐Ruiz (ORCID: https://orcid.org/0000-0002-8894-0501)
- Isabel del Cura-González (ORCID: https://orcid.org/0000-0002-3931-5304)
- María M. Morales‐Suárez Varela
- María Padilla‐Ruiz
- Manuel Macías
Institutions
- Instituto de Salud Carlos III (ES)
- Hospital Costa del Sol (ES)
- BioCruces Health research Institute (ES)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- Hospital Regional Universitario de Málaga (ES)
- Hospital de Galdakao (ES)
- Madrid Health Service (ES)
- Hospital Universitario Reina Sofía (ES)
- Institute of Research and Innovation Parc Tauli (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Hospital Clínico Universitario Virgen de la Victoria (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Colorectal Disease
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1111/codi.70250
- Citations
- 1
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Red de Investigación en Servicios de Salud en Enfermedades Crónicas
- Instituto de Salud Carlos III
- European Regional Development Fund