Maternal Genetic Variants in Kinesin Motor Domains Prematurely Increase Egg Aneuploidy
(Abstracted from Proc Natl Acad Sci U S A 2024;121(45):e2414963121) A complex network of gene interactions governs female fertility, with a large portion of successful fertility hinging on eggs of high quality and sufficient quantity. One aspect of quality is egg euploidy, which refers to correct chromosome complement; the less successful counterpart to this is aneuploidy, which can cause failure to implant or early miscarriage, as well as chromosomal disorders if a pregnancy is successfully carried to term.
Authors
- Jinchuan Xing (ORCID: https://orcid.org/0000-0001-6469-8733)
- Katarzyna M. Tyc (ORCID: https://orcid.org/0000-0002-3850-6934)
- Leelabati Biswas (ORCID: https://orcid.org/0000-0003-0341-5108)
- Kruno Vukušić (ORCID: https://orcid.org/0000-0002-4867-6080)
- Xin Tao (ORCID: https://orcid.org/0000-0001-9259-8326)
- Vanessa Guo
- Karen Schindler (ORCID: https://orcid.org/0000-0001-6113-1184)
- Iva M. Tolić (ORCID: https://orcid.org/0000-0003-1305-7922)
- Iva Dundović (ORCID: https://orcid.org/0000-0001-7770-2420)
- Min Xu (ORCID: https://orcid.org/0009-0009-1335-0580)
- Jason Liu (ORCID: https://orcid.org/0000-0003-2287-2320)
- Richard T. Scott (ORCID: https://orcid.org/0000-0002-2572-3980)
- Siqi Sun (ORCID: https://orcid.org/0000-0002-9592-3670)
- Mansour Aboelenaain
Publication Details
- Journal
- Obstetrical & Gynecological Survey
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1097/01.ogx.0001169636.66823.60
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00