The Burden of Surgical Site Infections With Pathogens Presumably Resistant to Perioperative Prophylaxis in Orthopedic Tumor Surgery: Secondary Analysis of the Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Trial
SSIs due to pathogens presumably resistant to the systemic or local prophylactic agents used are common in patients undergoing reconstruction for bone tumors. The selection of presumably resistant pathogens is not driven by the duration of antibiotic prophylaxis; however, antibiotic-loaded cement was associated with resistance.
Authors
- Dominik Mertz (ORCID: https://orcid.org/0000-0003-4337-1613)
- Michelle Ghert (ORCID: https://orcid.org/0000-0002-4778-4522)
- Sabine Kuster (ORCID: https://orcid.org/0000-0001-5549-9193)
- Caleb Gottlich (ORCID: https://orcid.org/0000-0001-7402-891X)
- Tim M. O’Shea (ORCID: https://orcid.org/0000-0002-0793-6915)
Institutions
- Texas Tech University (US)
- McMaster University Medical Centre (CA)
- Texas Tech University Health Sciences Center (US)
- McMaster University (CA)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1093/infdis/jiaf513
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00