Regulatory T-Cell Pioneers Awarded Nobel Prize

By identifying regulatory T cells, this year’s Nobel laureates revealed a paradox at the heart of immunity: The same cells that prevent autoimmunity also suppress anticancer responses. That insight is now fueling experimental therapies in oncology, though achieving the necessary selectivity has proven difficult.

Publication Details

Journal
Cancer Discovery
Published
2025-01-01
DOI
https://doi.org/10.1158/2159-8290.cd-nw2025-0082
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Regulatory T-Cell Pioneers Awarded Nobel Prize

Cancer Discovery
CAR-T cell therapy research
article

Regulatory T-Cell Pioneers Awarded Nobel Prize

article en

Abstract

By identifying regulatory T cells, this year’s Nobel laureates revealed a paradox at the heart of immunity: The same cells that prevent autoimmunity also suppress anticancer responses. That insight is now fueling experimental therapies in oncology, though achieving the necessary selectivity has proven difficult.

Cancer Discovery
Openalex Percentile: Top 62%
CAR-T cell therapy research
DOISourceOpenAlex
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Regulatory T-Cell Pioneers Awarded Nobel Prize · Cancer Discovery (2025) | TGRS Research Map | TGRS